604 Harmony Lane
Pleasantville, CA 94588
- Intensive experience in DNA and protein sequence analysis using GCG, BLAST, genefinder, ORFfinder, and Grail.
- Gene discovery, including protein domain identifications, EST blast, and unfinished sequence database mining.
- Proficient in structure-function relationship, both in experiments and molecular modeling based on three-dimensional structure using Sybyl and Insight II packages.
- Adept at structure-function relationship analysis (protein domain) based on primary sequences and PDB crystal structures.
- Development of applications for genomic sequencing data, including algorithms and implementation.
- Skilled at signature sequence analysis, including protein domains and protein family classification for protein and DNA sequences.
- Practiced at writing 3-tier applications development in microarray and sequence data analysis.
- Accomplished object-oriented programming language (OOPL) designer for applications development.
- Experienced in development of computer applications for genomic data analysis.
- Proficient in writing programs for microarray data analysis.
- Database design and implementation.
Pathobiology Department, University of Florida
Ph.D, Molecular Biology and Protein Chemistry, Pathobiology Department,
Computer and Information Science and Engineering Department, University of Florida, Gainesville, Florida
M.S., M.S., Computer and Information Science
KEY SUBJECT AREAS:
Software Testing, Programming Languages, Database Management
Computation Algorithms, Data Structure and Algorithms, and Computer Architecture
Entomology Department, Kasetsart University, Bangkok, Thailand
Entomology Department, Nanjing Agricultural University, Nanjing, China
• SYSTEMS - UNIX, Linux, Windows 95/98NT/2000, Macintosh
• LANGUAGES - Basic, C++, SQL, Java, Java Servlets, JSP, Perl, OOPL
• DATABASES - Oracle, Access
• APPLICATIONS - SAS, Oracle Tools, MS Office
• Developed DNA library of Anaplasma marginale.
• Purified, hybridized, and sequenced DNA of plamepsin genes from P. falciparum.
• Designed and implemented web-based application based on Microarray Database Management System (MDMS), using JAVA/JSP.
• Wrote applications for Malaria Genome Tag project, using Visual Basic.
• Developed diagnoses applications based on microarray data, using artificial neural network and Matlab.
• Built program for automating collection and analysis of kinetic data, using Visual Basic.
• Composed microarray transformation algorism based on entropy using Matlab.
• Developed application for screening of pest-resistant varieties of soybean.
• Constructed discriminate Analysis for micorarrary data using Visual Basic.
• Complied CPU performance data transformation program, using Perl.
• Assembled and implemented, MDMS using Oracle.
• Expressed, purified, and enzymatically assayed plasmepsins, a family of aspartic proteinases from malaria parasites.
• Mutated amino acid residues in plasmepsin sequence to test functions in vitro, based on analysis of structure-function relationship.
• Made molecular models of plasmepsins using Sybly for structure-functions relationship analysis.
• Designed established protocols for protein purification/quantification.
• Created established FPLC protocols for protein purification.
• Discovered three proteinase genes of P. falciparum.
• Developed kinetic assay for plamepsins.
2001 - Present
University, College of Veterinary Medicine
1995 - 2001
Academy of Agricultural Sciences
1986 - 1995
Academy of Agricultural Sciences
1985 - 1986
Presidential Recognition, University - 1997 and 1999
American Association for the Advancement of Science
American Society of Tropical Medicine and Hygiene
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